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Cenforce D has been approved by a clinical panel for use in treating male erectile dysfunction and problems associated with early ejaculation. Give yourself between 30 and 60 minutes before having sex. Sometimes using Cenforce D causes lightheadedness and vertigo. Sildenafil citrate, a phosphodiesterase (PDE-5) inhibitor, is the active ingredient of Cenforce D (100+60) mg tablets. It improves erectile dysfunction in men by widening penile veins and boosting blood flow to the penis.