Long-term use of capsaicin causes these neurons Sciatiease to become overstimulated and release all substance P until there is none left. This prevents pain signals from being sent to the brain. Eventually, these neurons become less sensitive to pain. Capsaicin may cause the following side effects at the application site (where the product is used): Burning Irritation Itching Red capsaicin may irritate the throat and cause sneezing or coughing. Lidocaine Lidocaine reduces nerve pain by blocking nerve cells from sending pain signals. Common side effects of lidocaine at the application Sciatiease Reviews site may include: Itching Pale skin with red patches Swelling Tenderness Basics Prescribing guidelines for sciatica remain controversial. Some research suggests that anti-inflammatory drugs may help people with sciatica. But there is no strong evidence to support most drugs. For some people, the combination of gabapentin and amitriptyline can further reduce sciatica pain. But side effects are common. If you have any questions or concerns about sciatica medications, ask your pharmacist or healthcare provider.
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