Fildena 25 mg is a medication primarily used to treat erectile dysfunction (ED) in men. It contains Sildenafil Citrate as its active ingredient, which belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Here’s how Fildena 25 mg works to improve blood flow and help men achieve and maintain an erection:
- Mechanism of Action: When a man is sexually stimulated, nitric oxide is released into the erectile tissue of the penis. This activates an enzyme called guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP), a chemical that relaxes the smooth muscles in the blood vessels of the penis. This relaxation allows increased blood flow, leading to an erection.
- Inhibition of PDE5: Sildenafil in Fildena 25 mg works by inhibiting the action of PDE5, an enzyme that breaks down cGMP. By inhibiting PDE5, Sildenafil helps to maintain higher levels of cGMP in the penis during sexual stimulation, promoting prolonged relaxation of the smooth muscles and increased blood flow to facilitate an erection.
- Onset and Duration: Fildena 25 mg typically starts working within 30 to 60 minutes after ingestion, although the onset may vary based on individual factors such as metabolism and whether it’s taken with food. The effects can last up to 4 to 6 hours, during which time sexual stimulation can lead to erections.
- Effectiveness: It is effective in a significant percentage of men with ED, providing them with the ability to achieve and sustain erections sufficient for satisfactory sexual activity.
- Usage Considerations: Fildena 25 mg should be taken as directed by a healthcare provider and should not be combined with other medications containing nitrates or recreational drugs like poppers, as this can cause a sudden and serious decrease in blood pressure.